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David Meigooni

Lexington, KY
Age 17

A Novel Method for Enhancing Prostate Cancer
Radiosensitization by Natural Compound Curcumin

Spencer Whale, invented KidKare hospital equpment
 

A Novel Method for Enhancing Prostate Cancer Radiosensitization by Natural Compound Curcumin

Curcumin (Diferuloylmethane) is a major component of turmeric, which is used as a spice to give a specific flavor and yellow color in Asian food. The application of curcumin as a method of making PC-3 prostate cancer cells more sensitive to radiation was investigated. Curcumin at 2uM and 4uM concentrations in combination with radiation showed significant enhancement (2.61 and 7.00, respectively) of the cancer cell death by inhibiting the survival factors and triggering mitochondrial degradation of the prostate cancer cells.

 
   
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The National Gallery for America's Young Inventors ™ is the only nationally recognized hall of fame for student inventors, established in 1993 and given permission by the adult National Inventors Hall of Fame Board in Washington, D.C. to archive and enshrine great student inventions and inventors K-12.
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